Exercise is a core treatment for most physiotherapists in all specialities. It is evidence-based and effective for most patient groups. 

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However, for people with ME there is a complex and adverse physiological response to exertion. This is why we do not recommend Graded Exercise Therapy for people with ME. 

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The table below compares normal physiological responses to exercise, with those found in people with ME.

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This table is taken from the International Consensus Primer, which includes references and more comprehensive details and can be read in full here

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