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Physiological Responses to Exercise
Exercise is a core treatment for most physiotherapists in all specialities. It is evidence-based and effective for most patient groups.
However, for people with ME there is a complex and adverse physiological response to exertion. This is why we do not recommend Graded Exercise Therapy for people with ME.
The table below compares normal physiological responses to exercise, with those found in people with ME.
This table is taken from the International Consensus Primer, which includes references and more comprehensive details and can be read in full here

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